A Histopathological Study on Gentamycin Induced Nephrotoxicity in Experimental Albino Rats
نویسندگان
چکیده
منابع مشابه
Nephroprotection of lacidipine against gentamycin-induced nephrotoxicity in albino rats.
AIM Gentamycin, a widely-used aminoglycoside antibiotic, is recognized as possessing significant nephrotoxic potential in human beings. Gentamycin-induced nephrotoxicity is suggested to be mediated via reactive oxygen species. The present study investigated the possible antioxidant nephroprotective effect of lacidipine as a calcium-channel blocker in a gentamycin-induced nephrotoxicity model in...
متن کاملGentamycin Induced Nephrotoxicity in Albino Mice
Twelve, male albino mice, aged 6-8 weeks, were injected intraperitoneally, aqueous solution of gentamicin (80 mg / kg / day) for fifteen days and the effects observed on the kidney structure and function. Group A served as control while Group B was given gentamicin. At the end of the experiment, blood was drawn from each animal by cardiac puncture for renal function tests and kidneys were fixed...
متن کاملStatins Induced Nephrotoxicity: a Dose Dependent Study in Albino Rats
Objective: The objective of the study was to evaluate the dose dependent effects of atorvastatin on rat kidneys. Methods: The selected doses of atorvastatin were administered orally for 17 days to rats. The statin induced nephrotoxicity was accessed by carrying out renal function tests and is by renal histopathology analysis. Measurements of antioxidant enzymes were also carried out to check wh...
متن کاملEXPERIMENTAL Trypanosoma Evansi INFECTION IN ALBINO MICE – A HISTOPATHOLOGICAL STUDY
Histopathological changes were studied in Swiss albino mice (N:36) which were challenged with the South Indian local strain of Trypanosoma evansi. Each animal was infected with 5×105 trypanosomes intraperitoneally. The animals were examined daily for development of clinical signs and infection status by wet blood-fi lms made from the tail veins. The infected mice were dull and depressed from tw...
متن کاملthe effect of aqueous extract of garlic on formalin-induced pain in male rats
چکیده اثر عصاره آبی سیر بر درد ناشی از آزمون فرمالین در موش صحرایی نر به کوشش نرگس اسکندری روزبهانی زمینه و هدف: گیاه سیر از خانواده لیلیاسه و گونهallium sativum بومی آسیای میانه بوده و از دوران ،باستان تاکنون به خواص درمانی متفاوت آن مثل: کاهندگی قندخون، کلسترول خون، فشار خون، اثرات مفیدآن بر دستگاه قلبی عروقی و بیماریهای انعقادی خون، اثرات آنتی اکسیداتیو، درمان بیماریهای تنفسی وگوارشی، ا...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: IOSR Journal of Dental and Medical Sciences
سال: 2012
ISSN: 2279-0861,2279-0853
DOI: 10.9790/0853-0111417